For research purposes only. Not for human consumption.
IGF-1 LR3 1mg is a recombinant elongated analogue of Insulin-like Growth Factor 1 (IGF-1), featuring an arginine substitution at position 3 and an additional 13-amino acid N-terminal extension. These structural modifications dramatically reduce binding affinity for IGF binding proteins (IGFBPs), resulting in a significantly extended biological half-life compared to native IGF-1, making it a highly useful tool for research into the IGF-1 signalling axis and anabolic cellular pathways.
Research employing IGF-1 LR3 has investigated its potent activation of the IGF-1 receptor (IGF1R) and the downstream PI3K/Akt/mTOR and MAPK/ERK signalling cascades. Studies have examined its influence on protein synthesis, cellular hypertrophy, satellite cell activation, and glucose uptake. The reduced IGFBP binding is especially valuable for research designs requiring sustained IGF-1 receptor occupancy, and it has been used widely in muscle biology, metabolic research, and cellular growth studies.
Supplied as a high-purity white lyophilised powder, this product exceeds >99% purity as verified by HPLC analysis. Its freeze-dried formulation ensures long-term structural stability, maintaining peptide integrity throughout storage and transport. Researchers may reconstitute the compound using bacteriostatic water or a sterile diluent suited to their experimental protocol.
IGF-1 LR3 1mg is intended exclusively for in vitro and non-clinical scientific research. It is not approved for human or animal therapeutic, diagnostic, or medicinal use. All handling and experimentation must be conducted by trained professionals within appropriate controlled laboratory environments.
Certificate status: This product's third-party Certificate of Analysis has been ordered and is currently in progress. The verified report will be published here once available.
Pending publication of the finalized third-party laboratory report.
Disclaimer: All products supplied by Ultima Labs are intended solely for laboratory and scientific research purposes. These products are not licensed, approved, or meant for human or animal consumption, nor for any form of therapeutic, medicinal, or diagnostic use. The information presented on this website has not undergone evaluation or approval by the Therapeutic Goods Administration (TGA) or any other regulatory authority. These compounds are not formulated to diagnose, treat, cure, or prevent any disease or health condition. Purchase is limited to qualified professionals, researchers, and authorized research institutions both within Australia and internationally. By placing an order, you acknowledge and agree to comply with these terms.